To add to Robert's comments...
The numero uno issue I see with any Holley modular carb, whether new out of the box, a unit that is in service, or a carb sent in for overhaul is loose fasteners!
These (and most all) carburetors are manufactured from components made from cast aluminum, cast zinc, and steel fasteners. Three different "expansion" rates as their respective temperatures change when in operation. That's compounded by heat from the intake manifold, and the chilling effect of vaporizing gasoline.
When I remove new carbs from their packaging for modification/preparation, I go over all fasteners and really tighten down. Scruu the "torque specs"! The gaskets settle over time, and are definitely affected by liquid fuel exposure, though the "blue" gaskets used in Holley production stuff the last several years are affected to a lesser degree.
Same for reconditioning these mixers, all fasteners get cranked to just below the point of stripping. Ya just gotta "feel" that point and if ya miss the target...then that is what heli-coils are made for. Nearly every carb I send out has at least one heli-coil somewhere.
This e10 shit-for-gas compounds this issue as that crap will deteriorate sealing elements at an unknown rate. At this point we don't know what is happening completely, every day I see carbs with "different" issues" which I believe to be "root cause" by this alkeeshit. I'm documenting all that now and will do a write up as soon as I have enough definitive information gathered.
Regarding the e10 "pr"-bullshit, dont believe a word of it. We had/saw the same thing happen back in the 1973>1978 timeframe when the first release of "gasahol" came about. It took more than ten years for the aftermarket parts industry to phase in materials that were not affected by gasahol. The "market" and the government only care about vehicles produced in the last few years since they think everyone only drives a "new" transport device.
An example of this is the fact that the "black" Holley accel pump elements will deteriorate within a year when exposed to e10. The use of the "green" gflt accel pump is mandatory with this e10 shit now, which adds to the expense of an overhaul.
The fasteners that retain the throttle body to the main body must be cranked to just under the point of strippage. Otherwise they will loosen over time, resulting in internal vacuum and liquid leakage. I also now use red thread locker on those fasteners.
Ya can't tighten the four bowl screws that tight as you are compressing two gaskets plus the sealing washers under the screw heads. But if you pull the bowl and metering block off, I bet you will see a gasket that is distorted inna critical area as you described. Replace the gaskets after cleaning all sealing surfaces, and then tighten the bowl screw alternately inna cris-cross pattern real tight!
And for those that think that "electronic"-control fuel injection schnizz is immune to this same kinda e10-induced crap, then you are just fooling yoreself! There are all kindsa "composite" materials in the throttle body assemblies, same for the fuel storage and delivery systems.